Studies: Assessments of brain electrical activity in both humans and animals have shown that boron deprivation—0.12 μg/g in the diet as boric acid—results in decreased brain electrical activity.70 In mature rats, boron deprivation was associated with decreased high-frequency and increased low-frequency brain electrical activity, consistent with decreased arousal, suggesting that boron may play an important role in the maintenance of brain activation in animals. In humans, boron deprivation (less than 0.3 mg/d) resulted in poorer performance on tasks of motor speed and dexterity, attention, and short-term memory. A series of experiments conducted in otherwise healthy older men and women found that relatively short periods, 42 to 73 days, of restricted boron intake adversely affected brain function and cognitive performance. The most consistent EEG finding was that low boron intake resulted in a shift toward more activity in the low frequencies and less activity in the high, dominant frequencies of the EEG spectrum, the same effect typically observed in response to nonspecific malnutrition and heavy-metal toxicity. Increased low frequency activity is characteristic of states of reduced mental alertness, is associated with lowered ability to perform vigilance and psychomotor tasks, and has been related to impaired memory performance.
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